Risk of GLP Medications

Risk of GLP-Medications

Glucagon-like peptide-1 (GLP-1) receptor agonists, commonly prescribed for managing type 2 diabetes and obesity, have potential risks and side effects, including:

1. Gastrointestinal Issues: Nausea, vomiting, diarrhea, or constipation are the most common side effects, particularly when starting the medication or adjusting the dose.

2. Hypoglycemia: Although rare, especially when used alone, the risk increases if taken with other glucose-lowering medications like insulin or sulfonylureas.

3. Pancreatitis: There is a potential risk of acute pancreatitis, which may present as severe abdominal pain.

4. Gallbladder Issues: An increased risk of gallbladder disease, including gallstones, has been reported.

5. Thyroid Tumors: Some animal studies suggest a risk of thyroid C-cell tumors, though this risk in humans is unclear.

6. Kidney Problems: Dehydration from side effects like vomiting or diarrhea can lead to kidney injury in some cases.

7. Allergic Reactions: Rarely, individuals may experience hypersensitivity or allergic reactions, including rash, swelling, or difficulty breathing.

8. Heart Rate Changes: Some users report an increase in resting heart rate, which may be a concern for those with cardiovascular conditions.